/* Hotspot — a sequencer printout.
   Thermal chart paper with a millimetre grid, four trace inks (A green,
   C blue, G black, T red), condensed instrument lettering, mono read-outs.
   Mobile first: everything is laid out for 390 px and widened above 720 px. */
:root {
  color-scheme: light;
  --paper: #eef3ec;
  --paper-2: #e3ebdf;
  --paper-3: #f7faf5;
  --grid: rgba(38, 104, 62, .085);
  --grid-major: rgba(38, 104, 62, .17);
  --ink: #17201a;
  --ink-2: #49584e;
  --ink-3: #7b8a80;
  --rule: #b9c9b6;
  --A: #22924a;
  --C: #1d5cc2;
  --G: #17201a;
  --T: #d23229;
  --amber: #b97c00;
  --hot: #d23229;
  --display: 'Barlow Condensed', 'Arial Narrow', sans-serif;
  --body: 'Barlow', system-ui, sans-serif;
  --mono: 'IBM Plex Mono', ui-monospace, Menlo, monospace;
  /* SBS-96 class colours: the convention every signature figure uses */
  --s-CA: #1ebff0; --s-CG: #050708; --s-CT: #e62725; --s-TA: #b9b8b9; --s-TC: #a1cf64; --s-TG: #e8b9b5;
}
* { box-sizing: border-box; }
[hidden] { display: none !important; }
html { -webkit-text-size-adjust: 100%; }
html, body { margin: 0; }
body {
  background-color: var(--paper);
  background-image:
    linear-gradient(var(--grid-major) 1px, transparent 1px),
    linear-gradient(90deg, var(--grid-major) 1px, transparent 1px),
    linear-gradient(var(--grid) 1px, transparent 1px),
    linear-gradient(90deg, var(--grid) 1px, transparent 1px);
  background-size: 60px 60px, 60px 60px, 12px 12px, 12px 12px;
  color: var(--ink);
  font: 400 16px/1.5 var(--body);
  min-height: 100vh;
  overflow-x: hidden;
}
a { color: var(--C); text-underline-offset: 2px; }
button, input, select { font: inherit; color: inherit; }
button { cursor: pointer; }
:focus-visible { outline: 2px solid var(--C); outline-offset: 2px; }

.wrap { max-width: 980px; margin: 0 auto; padding: 0 16px calc(32px + env(safe-area-inset-bottom)); }

/* ---- printer head: brand row ---- */
.head { display: flex; align-items: flex-end; justify-content: space-between; gap: 12px; padding: 14px 0 8px; border-bottom: 2px solid var(--ink); }
.brand { text-decoration: none; color: var(--ink); display: block; }
.brand b { font: 700 34px/0.9 var(--display); letter-spacing: .02em; display: block; text-transform: uppercase; }
.brand span { font: 500 10.5px/1.3 var(--mono); color: var(--ink-2); letter-spacing: .04em; text-transform: uppercase; display: block; margin-top: 4px; }
.keys { display: flex; gap: 4px; }
.key { display: inline-flex; align-items: center; justify-content: center; min-height: 40px; min-width: 52px; padding: 0 10px; border: 1.5px solid var(--ink); background: var(--paper-3);
  font: 600 15px/1 var(--display); letter-spacing: .06em; text-transform: uppercase; color: var(--ink); text-decoration: none; box-shadow: 0 2px 0 var(--ink); }
.key[aria-current="page"], .key.on { background: var(--ink); color: var(--paper); }
.key:active { transform: translateY(2px); box-shadow: none; }

/* ---- run label strip (like the header of a trace printout) ---- */
.run { display: flex; flex-wrap: wrap; gap: 4px 14px; font: 500 11px/1.4 var(--mono); color: var(--ink-2); text-transform: uppercase; letter-spacing: .03em; padding: 6px 0; border-bottom: 1px dashed var(--rule); }
.run b { color: var(--ink); font-weight: 500; }

/* ---- hero chromatogram ---- */
.trace { margin: 14px 0 4px; }
.trace svg { display: block; width: 100%; height: auto; }
.trace figcaption { font: 400 12px/1.45 var(--mono); color: var(--ink-2); margin-top: 4px; }
.lede { font: 500 19px/1.35 var(--body); margin: 10px 0 4px; max-width: 34em; }
.lede em { font-style: normal; color: var(--T); }

/* ---- sections ---- */
.sec { margin-top: 26px; }
.lane { display: flex; align-items: baseline; gap: 10px; border-top: 2px solid var(--ink); padding-top: 6px; margin-bottom: 10px; }
.lane .no { font: 500 11px var(--mono); color: var(--ink-2); white-space: nowrap; }
.lane h2 { font: 700 24px/1.05 var(--display); text-transform: uppercase; letter-spacing: .02em; margin: 0; }
.note { font-size: 14px; color: var(--ink-2); margin: 4px 0 10px; }
.mono { font-family: var(--mono); }
.small { font-size: 13px; }

/* ---- search ---- */
.search { position: relative; margin-top: 14px; }
.search label { display: block; font: 600 13px var(--display); letter-spacing: .08em; text-transform: uppercase; color: var(--ink-2); margin-bottom: 4px; }
.field { display: flex; border: 2px solid var(--ink); background: var(--paper-3); }
.field span { font: 500 15px var(--mono); padding: 0 10px; display: flex; align-items: center; background: var(--ink); color: var(--paper); }
.field input { flex: 1; min-width: 0; border: 0; background: transparent; padding: 12px 10px; font: 500 18px var(--mono); text-transform: uppercase; outline: none; }
.field button { border: 0; border-left: 2px solid var(--ink); background: var(--T); color: #fff; font: 700 16px var(--display); letter-spacing: .08em; padding: 0 14px; text-transform: uppercase; }
.sugg { list-style: none; margin: 0; padding: 0; position: absolute; left: 0; right: 0; top: 100%; z-index: 5; background: var(--paper-3); border: 2px solid var(--ink); border-top: 0; max-height: 50vh; overflow-y: auto; }
.sugg li button { display: flex; justify-content: space-between; width: 100%; border: 0; background: none; padding: 11px 12px; font: 500 15px var(--mono); text-align: left; border-bottom: 1px dashed var(--rule); }
.sugg li button:hover, .sugg li button[aria-selected="true"] { background: var(--paper-2); }
.sugg small { color: var(--ink-3); font-size: 12px; }
.chips { display: flex; flex-wrap: wrap; gap: 6px; margin-top: 8px; }
.chip { border: 1px solid var(--ink-2); background: transparent; padding: 6px 10px; min-height: 36px; font: 500 13px var(--mono); color: var(--ink); text-decoration: none; display: inline-flex; align-items: center; }

/* ---- lists that read like a call log ---- */
.log { list-style: none; margin: 0; padding: 0; counter-reset: n; }
.log li { border-bottom: 1px dashed var(--rule); }
.log a, .log .row { display: grid; grid-template-columns: 26px 1fr auto; gap: 2px 10px; align-items: baseline; padding: 9px 2px; color: var(--ink); text-decoration: none; }
.log .rk { font: 500 11px var(--mono); color: var(--ink-3); }
.log .nm { font: 600 18px/1.15 var(--display); letter-spacing: .02em; }
.log .nm i { font-style: normal; color: var(--T); }
.log .val { font: 500 13px var(--mono); text-align: right; white-space: nowrap; }
.log .sub { grid-column: 2 / 4; font: 400 12px/1.35 var(--mono); color: var(--ink-2); overflow-wrap: anywhere; }

.qv { font-family: var(--mono); white-space: nowrap; }

/* ---- type grid ---- */
.types { display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); gap: 6px; }
.tcard { display: block; border: 1.5px solid var(--ink); background: var(--paper-3); padding: 8px 9px; color: var(--ink); text-decoration: none; min-height: 72px; }
.tcard b { font: 700 20px/1 var(--display); letter-spacing: .03em; }
.tcard span { display: block; font-size: 12px; line-height: 1.25; color: var(--ink-2); margin-top: 3px; }
.tcard small { display: block; font: 400 11px var(--mono); color: var(--ink-2); margin-top: 4px; }
.tcard .bar { display: flex; height: 6px; margin-top: 6px; background: var(--paper-2); }
.tcard .bar i { display: block; height: 100%; }

/* ---- plots ---- */
.plot { position: relative; background: var(--paper-3); border: 1.5px solid var(--ink); padding: 6px 4px 2px; }
.plot svg { display: block; width: 100%; height: auto; touch-action: manipulation; user-select: none; -webkit-user-select: none; }
.legend { display: flex; flex-wrap: wrap; gap: 4px 12px; font: 500 12px var(--mono); margin: 6px 0 0; color: var(--ink-2); }
.legend i { display: inline-block; width: 10px; height: 10px; border-radius: 50%; margin-right: 4px; vertical-align: -1px; }
.readout { font: 400 13px/1.45 var(--mono); background: var(--ink); color: var(--paper); padding: 8px 10px; margin-top: 6px; min-height: 40px; overflow-wrap: anywhere; }
.readout b { color: #ffd166; font-weight: 500; }
.ctl { display: flex; flex-wrap: wrap; gap: 8px; align-items: center; margin: 8px 0; }
.ctl select { border: 1.5px solid var(--ink); background: var(--paper-3); padding: 8px 8px; min-height: 42px; font: 500 14px var(--mono); max-width: 100%; }
.tog { border: 1.5px solid var(--ink); background: var(--paper-3); min-height: 42px; padding: 0 12px; font: 600 14px var(--display); letter-spacing: .06em; text-transform: uppercase; }
.tog[aria-pressed="true"] { background: var(--ink); color: var(--paper); }

/* ---- gene header ---- */
.gh { display: flex; flex-wrap: wrap; align-items: baseline; gap: 2px 12px; margin-top: 14px; }
.gh h1 { font: 700 46px/0.95 var(--display); margin: 0; letter-spacing: .01em; }
.gh .meta { font: 400 12px/1.45 var(--mono); color: var(--ink-2); }
.big-n { font: 700 28px/1 var(--display); }

/* ---- tables in their own scroll ---- */
.tbl { overflow: auto; max-height: 420px; border: 1.5px solid var(--ink); background: var(--paper-3); -webkit-overflow-scrolling: touch; }
.tbl table { border-collapse: collapse; width: 100%; font: 400 12.5px/1.35 var(--mono); }
.tbl th, .tbl td { padding: 6px 8px; border-bottom: 1px dashed var(--rule); text-align: left; vertical-align: top; white-space: nowrap; }
.tbl th { position: sticky; top: 0; background: var(--ink); color: var(--paper); font-weight: 500; z-index: 1; }
.tbl td.wrap { white-space: normal; min-width: 150px; }
.tbl tr.hs td:first-child { color: var(--T); font-weight: 500; }
.btn { display: inline-flex; align-items: center; justify-content: center; gap: 8px; min-height: 48px; padding: 0 18px; border: 2px solid var(--ink); background: var(--ink); color: var(--paper);
  font: 700 17px/1 var(--display); letter-spacing: .08em; text-transform: uppercase; text-decoration: none; box-shadow: 0 3px 0 var(--T); }
.btn.ghost { background: var(--paper-3); color: var(--ink); box-shadow: 0 3px 0 var(--ink); }
.btn.full { width: 100%; }
.btn:disabled { opacity: .35; box-shadow: none; }
.btn:active:not(:disabled) { transform: translateY(2px); box-shadow: none; }

/* ---- per-type bars ---- */
.bars { display: grid; gap: 4px; }
.bars a, .bars div.b { display: grid; grid-template-columns: 52px minmax(0, 1fr) auto; gap: 8px; align-items: center; color: var(--ink); text-decoration: none; min-height: 30px; }
.bars b { font: 700 15px var(--display); letter-spacing: .03em; }
.bars .track { height: 12px; background: repeating-linear-gradient(90deg, var(--paper-2) 0 9px, var(--rule) 9px 10px); position: relative; }
.bars .track i { position: absolute; left: 0; top: 0; bottom: 0; background: var(--ink); }
.bars span { font: 400 12px var(--mono); text-align: right; white-space: nowrap; }

/* ---- signatures ---- */
.sigs { display: grid; grid-template-columns: minmax(0, 1fr); gap: 10px; }
.sig { border: 1.5px solid var(--ink); background: var(--paper-3); padding: 8px; }
.sig h3 { margin: 0; font: 700 18px/1.1 var(--display); letter-spacing: .02em; }
.sig h3 small { font: 500 11px var(--mono); color: var(--ink-2); margin-left: 6px; letter-spacing: 0; }
.sig p { margin: 2px 0 4px; font: 400 12px/1.35 var(--mono); color: var(--ink-2); }
.sig svg { display: block; width: 100%; height: auto; }
.fam { display: inline-block; font: 600 12px/1 var(--display); letter-spacing: .06em; text-transform: uppercase; padding: 3px 6px; border: 1px solid currentColor; }

.foot { margin-top: 36px; padding-top: 10px; border-top: 2px solid var(--ink); font-size: 13px; color: var(--ink-2); }
.foot p { margin: 6px 0; }
.err { border: 2px solid var(--T); color: var(--T); padding: 10px; font: 500 14px var(--mono); margin-top: 12px; }
.load { font: 500 13px var(--mono); color: var(--ink-2); padding: 18px 0; }

/* ---- game ---- */
.hud { display: flex; gap: 6px; align-items: center; }
.pill { border: 1.5px solid var(--ink); padding: 4px 8px; font: 500 13px var(--mono); background: var(--paper-3); white-space: nowrap; }
.modes { display: grid; grid-template-columns: 1fr 1fr; gap: 6px; margin-top: 12px; }
.modes .key { min-height: 46px; }
.card { border: 2px solid var(--ink); background: var(--paper-3); padding: 12px; margin-top: 12px; }
.card .q { font: 700 25px/1.08 var(--display); margin: 2px 0 6px; }
.card .q i { font-style: normal; color: var(--T); }
.card .meta { font: 400 12px/1.4 var(--mono); color: var(--ink-2); }
.pick { font: 500 14px/1.4 var(--mono); margin-top: 8px; min-height: 40px; }
.pick b { color: var(--T); font-weight: 500; }
.res { border: 2px solid var(--ink); border-top-width: 6px; padding: 10px 12px; margin-top: 10px; background: var(--paper-3); }
.res .pts { float: right; font: 700 34px/1 var(--display); color: var(--T); }
.res h3 { margin: 0; font: 700 20px/1.1 var(--display); }
.res p { margin: 6px 0 0; font-size: 15px; }
.res .why { font-size: 14px; color: var(--ink-2); }
.opts { display: grid; grid-template-columns: 1fr 1fr; gap: 6px; margin-top: 10px; }
.opt { min-height: 54px; border: 2px solid var(--ink); background: var(--paper-3); font: 700 16px/1.1 var(--display); letter-spacing: .03em; text-transform: uppercase; padding: 6px; }
.opt.right { background: var(--A); color: #fff; border-color: var(--A); }
.opt.wrong { background: var(--T); color: #fff; border-color: var(--T); }
.opt:disabled { cursor: default; }
.end { text-align: center; border: 2px solid var(--ink); background: var(--paper-3); padding: 16px 12px; margin-top: 14px; }
.end .total { font: 700 64px/1 var(--display); color: var(--T); margin: 6px 0 2px; }
.end ul { list-style: none; padding: 0; margin: 10px 0; text-align: left; }
.end li { display: flex; justify-content: space-between; gap: 8px; padding: 7px 0; border-bottom: 1px dashed var(--rule); font: 400 13px var(--mono); }
.end pre { font: 400 13px/1.4 var(--mono); background: var(--paper-2); padding: 8px; white-space: pre-wrap; text-align: left; }

/* drop animation for the reveal */
.drop { transform: translateY(var(--from, -160px)); opacity: 0; }
.dropped { transform: none; opacity: 1; transition: transform .55s cubic-bezier(.3, 1.35, .5, 1), opacity .2s; }
@media (prefers-reduced-motion: reduce) {
  .drop { transform: none; opacity: 1; }
  .dropped { transition: none; }
  * { scroll-behavior: auto !important; }
}

@media (min-width: 720px) {
  .brand b { font-size: 44px; }
  .types { grid-template-columns: repeat(4, minmax(0, 1fr)); }
  .sigs { grid-template-columns: repeat(2, minmax(0, 1fr)); }
  .two { display: grid; grid-template-columns: 1fr 1fr; gap: 24px; }
  .gh h1 { font-size: 60px; }
  .opts { grid-template-columns: repeat(3, 1fr); }
}